HORDB

ID: hor006271
Uniprot ID: Q18060
Protein name: A-chain-like peptide
Gene name: ins-11
Organism: Caenorhabditis elegans
Family: Insulin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa , Protostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: NA
GO BP: GO:0045087 innate immune response
GO CC: GO:0005576 extracellular region

Sequence: TASDCCRESCSLTEMLASCTLTSSEESTRDI
Length: 31(61-91)
Propeptide: MSSYRQTLFILIILIVIILFVNEGQGAPHHDKRHTACVLKIFKALNVMCNHEGDADVLRRTASDCCRESCSLTEMLASCTLTSSEESTRDI
Signal peptide: MSSYRQTLFILIILIVIILFVNEGQG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006271_AF2.pdb

hor006271_ESM.pdb

Mass:	386592	Formula:	C128H217N37O56S5
Absent amino acids:	FGHKNPQVWY	Common amino acids:	S
pI:	3.84	Basic residues:	2
Polar residues:	16	Hydrophobic residues:	6
Hydrophobicity:	-24.84	Boman Index:	-8040
Half-Life:	7.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	56.77
Instability Index:	8280.65	Extinction Coefficient cystines:	250
Absorbance 280nm:	8.33

PubMed ID: 9851916
Title: Genome sequence of the nematode C. elegans: a platform for investigating biology.
PubMed ID: 9548970
Title: New insulin-like proteins with atypical disulfide bond pattern characterized in Caenorhabditis elegans by comparative sequence analysis and homology modeling.